18:00 – onsdag 20 February
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Sevilla 2-0 SS Lazio
Fulltid
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| 84' |  | Ciro Immobile |
Marko Rog Roque Mesa |  | 81' |
| 2-0 Pablo Sarabia |  | 78' |
| 76' | | Riza Durmisi Milan Badelj |
| 71' |  | Adam Marušić |
Ibrahim Amadou André Silva | | 63' |
| Franco Vázquez |  | 60' |
| 56' | | Rômulo Sergej Milinkovic-Savic |
| 48' | | Joaquín Correa Patric |
| Halvtid 1-0 | ||
| 31' | | Felipe Caicedo |
| 21' | | Patric |
| 1-0 Wissam Ben Yedder | | 20' |
| Franco Vázquez | | 18' |
Quincy Promes Sergio Escudero | | 6' |
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